Plague vaccine research and development

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Plague Vaccine Development: Current Research and Future Trends

Plague is one of the world's most lethal human diseases caused by Yersinia pestis, a Gram-negative bacterium. Despite overwhelming studies for many years worldwide, there is no safe and effective vaccine against this fatal disease. Inhalation of Y. pestis bacilli causes pneumonic plague, a fast growing and deadly dangerous disease. F1/LcrV-based vaccines failed to provide adequate protection in...

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Current Vaccine Development against Plague

Yersinia pestis, the causative organism of the plague, has played an important role in shaping human history. Plague is an illness that may manifest in bubonic, pneumonic, or septicemic form. Natural outbreaks devastated entire populations in medieval times and an estimated 200 million humans were killed by plague throughout history. The organism can still be found today throughout the world, i...

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A Sensitised Anti-Plague Vaccine

it 011 a larger scale and I should be much obliged if you would publish this with the request that medical officers who are in charge of plague cases and are willing to try it, would communicate with me when I shall be pleased to send them some. The vaccine was made in the District Laboratory by kind permission of the A. D. P. H. of the N. W. F. Province. I would ask them when writing, to let m...

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Anti-Plague Vaccine in the Treatment of Plague

venous injections of iodine in this disease has been recognized by previous workers, I used it as a routine measure, giving injections containing from 2 to 1? grs. In spite of these injections most patients showed severe constitutional disturbances within 48 hours of commencing treatment, with delirium and restlessness. Severe asthenia would set in about the third day of treatment, and the prog...

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Schistosomiasis Vaccine: Research to Development

Due to their worldwide importance for human and animal health, schistosomes are in the focus of national and international research activities. Schistosomiasis is a major health problem and despite decades of research, only one effective drug, Praziquantel is currently available. Recent expansion of sequence databases on Schistosoma mansoni and S. japonicum has permitted a wealth of novel prote...

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ژورنال

عنوان ژورنال: Journal of Applied Microbiology

سال: 2001

ISSN: 1364-5072,1365-2672

DOI: 10.1046/j.1365-2672.2001.01497.x